The first latent green fluorophores for the detection of azoreductase activity in bacterial cultures.

نویسندگان

  • Arnaud Chevalier
  • Claire Mercier
  • Laura Saurel
  • Sylvain Orenga
  • Pierre-Yves Renard
  • Anthony Romieu
چکیده

An efficient synthesis of original bio-reductive probes suitable for the detection of azoreductases from the fluorescent rhodamine 110 dye is presented. A "turn-on" green fluorescence response upon reduction of the two diazo bonds of these latent fluorophores was observed both in vitro and in the context of bacterial cultures.

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عنوان ژورنال:
  • Chemical communications

دوره 49 78  شماره 

صفحات  -

تاریخ انتشار 2013